Methylation of miR-155-3p in mantle cell lymphoma and other non-Hodgkin's lymphomas
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چکیده
منابع مشابه
Methylation of miR-155-3p in mantle cell lymphoma and other non-Hodgkin's lymphomas
Mantle cell lymphoma (MCL) is an aggressive B-cell non-Hodgkin's lymphoma (NHL). In cancers, tumor suppressive microRNAs may be silenced by DNA hypermethylation. By microRNA profiling of representative EBV-negative MCL cell lines before and after demethylation treatment, miR-155-3p was found significantly restored. Methylation-specific PCR, verified by pyrosequencing, showed complete methylatio...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2014
ISSN: 1949-2553
DOI: 10.18632/oncotarget.2390